How is nephrotic syndrome caused?

summary

The typical manifestations of nephrotic syndrome are massive proteinuria (> 3.5 g / 1.73 M2 body surface area per day), hypoalbuminemia (plasma albumin < 30 g / L), hyperlipidemia and edema. These manifestations are directly or indirectly related to the increased filtration of plasma albumin by glomerular filtration membrane, resulting in the loss of a large amount of protein from urine. How is nephrotic syndrome caused?

How is nephrotic syndrome caused?

First: long term urinary retention is not only easy to cause bladder injury, but also easy to cause bacterial reproduction. Once it flows back to the ureter and kidney, the toxic substances in it will cause renal infection, leading to urinary tract infection, kidney disease and even uremia

Second: kidney disease caused by drug abuse is common. Many cold medicines, anti-inflammatory painkillers, weight-loss medicines and Chinese herbal medicines have nephrotoxicity, and these medicines are very common and widely used. People without medical knowledge tend to have dangerous symptoms when taking medicines themselves. Obese people are prone to hypertension, diabetes and other chronic diseases. If these chronic diseases are not well controlled, in the long run, it is easy to damage the kidney and indirectly lead to nephrotic syndrome

Third: too much salt is easy to cause kidney disease. The main component of salt is sodium chloride. Sodium is the mineral nutrient necessary for human body. Chlorine has a certain effect on the production and maintenance of the gastric acid and the osmotic pressure of human blood. However, the excessive sodium content in human body can cause the body to accumulate water, produce edema, increase blood volume and arteriole tension, and lead to blood pressure rise. Therefore, the incidence rate of hypertension is high in those with high salt. Hypertension is very easy to complicated with nephropathy.

matters needing attention

1. Fat: Patients with nephrotic syndrome are often accompanied with hyperlipidemia; For the patients with refractory nephrotic syndrome such as membranous nephropathy, long-term hyperlipidemia can cause arteriosclerosis. Therefore, it is necessary to limit hoof fat and food rich in animal fat. 2. Restriction: pay attention to the four major diets of nephrotic syndrome according to the degree of edema of the patient, avoid salt for those with high edema, and low salt (about 3 grams per day) for those with reduced edema but not enough. When the edema subsides and the plasma protein returns to normal, you can give normal diet.