What symptom does fibrocartilage stromal tumor have?

summary

What symptom does fibrocartilage stromal tumor have? Fibrocartilage stromal tumor is composed of two kinds of different tissues. One is cartilage like tissue, which is benign and similar to the growing epiphyseal plate; The other is similar to low-grade fibrosarcoma, which is rare. Most of them were male, aged from 9 to 23 years (average 13 years).

What symptom does fibrocartilage stromal tumor have?

Common symptoms: regular and hard bone swelling with clear boundary is common in men, aged from 9 to 23 years (average 13 years). It is located in the metaphysis of the proximal fibula, and only affects the epiphysis in adulthood. The tumor grows slowly and may have mild discomfort and tenderness. If it is located in the superficial bone, regular and hard bone swelling with clear boundary can be seen.

By naked eyes, the tumor was hard, white, bundle like appearance, similar to desmoid tumor or low-grade malignant fibrosarcoma, with cartilage like substance in the matrix, showing a special spiral, like growth cartilage plate. The etiology of this disease is unknown. It is speculated that it may be related to environmental, genetic, trauma, nutrition and other factors.

Microscopically, there were continuous and crossed spindle cells and collagen fiber bundles. In the tumor tissue, the nuclei were plump, pleomorphic and hyperchromatic. Mitotic images were rare. There were well-defined cartilage islands in the matrix. These cartilage differentiated well, which were benign manifestations. They often formed a thick wavy band, similar to the epiphyseal plate, with progressive columnar, proliferative and endochondral ossification, In short, the main component of fibrochondrostromal tumor is similar to that of grade I fibrosarcoma, and another distinct component is similar to that of epiphyseal plate, suggesting that it is a benign, organoid, hamartoma.

matters needing attention

The course of disease is slow, but the low base malignant tumor often has local recurrence after intralesional resection, even after a few years of operation. The primary tumor and recurrent tumor should be treated by tumor resection, and no metastasis has been reported. Treatment of fibrocartilage stromal tumor: surgical treatment; Drug therapy, radiation therapy.