What reason is psoriasis formed
summary
My cousin began to think that her skin was only suffering from dermatitis, so she used dermatitis to wipe it continuously. As a result, it had no effect at all. Later, she had to go to the hospital. Because she went to the hospital and received professional dermatology treatment, she learned what causes psoriasis. Here is her experience:
What reason is psoriasis formed
What reason is psoriasis formed? Immune disorder is one of the causes. The relationship between psoriasis and immunity has been widely valued. Psoriasis patients have a variety of local or systemic immune dysfunction. The disease is highly correlated with the expression of HLA B17 and other antigens, which indicates that psoriasis is also an immune disease. At present, the immune pathogenesis of the disease is not fully clear. More popular view is that psoriasis is caused by activated T cells of epidermal cell proliferation disease. There are activated T cells infiltrating in the dermis of psoriasis lesions. These cells release interferon - γ, induce epidermal cells to synthesize tumor necrosis factor, interleukin-8, interleukin-6, cytokines, etc., and attract neutrophils to infiltrate in the epidermis, leading to dermal vascular dilation and skin inflammation. In addition, IL-6 and IL-8 released by monocytes and epidermal cells also promote the proliferation of epidermal cells. Therefore, the pathological characteristics of the coexisting of epidermal dysplasia and skin inflammation were formed in the lesions. Further study is needed on the initiating factors of T cell activation in psoriasis lesions. It may be related to infection, trauma and neuropsychiatric factors.
What reason is psoriasis formed? Infection is the second cause. Clinical practice has proved that the incidence of psoriasis is related to upper respiratory tract infection and tonsillitis. 6% of psoriasis patients had a history of pharyngeal infection. We found that psoriasis in many children is closely related to tonsillitis. For example, a mother and her three children suffered from acute tonsillitis at the same time. After the disease was controlled, three people developed psoriasis. The patient was treated with antibiotics. After tonsillectomy, the rash can be significantly improved or subsided, indicating that infection is an important factor in the pathogenesis of psoriasis.
What reason is psoriasis formed? Heredity is the third cause. According to clinical findings, psoriasis often has a family history and genetic tendency. In foreign countries, 30% - 50% of them had family history, and even 100% of them were emphasized by some individuals. About 10% ～ 20% of the cases with family history have been reported in China. Some people think it is autosomal dominant inheritance with incomplete penetrance, while others think it is autosomal dominant inheritance. Recessive inheritance or sex linked inheritance. One of the parents is psoriasis, and the incidence rate of their offspring is 3 times higher than that of the healthy children. If both parents suffer from psoriasis, their offspring will have a higher incidence rate.
matters needing attention
It can be said that the pathogenesis of psoriasis is diverse, not determined by a single factor. In addition to the above genetic, infection and other factors, immune abnormalities, fat or sugar metabolism disorders, mental stimulation, trauma, seasonal changes and endocrine, hemorheological changes, some drugs, such as propranolol, are involved in the onset of the disease, or make the disease worse. Therefore, patients with psoriasis in daily life should pay attention to avoid trauma, prevent infection, keep optimistic mood to prevent the recurrence and development of lesions. Don't give yourself too much pressure, keep the mood happy and relaxed, the treatment of psoriasis has great help.
