Symptoms of bone metastasis from colon cancer

summary

In recent years, with the continuous improvement of people's living standard, changes in diet and diet structure and aging of population, the incidence rate and mortality rate of colorectal cancer in China have been increasing. Most patients have been found in middle and late stages. Liver metastasis, lung metastasis, abdominal metastasis are common, bone metastasis is rare. Let's talk about the symptoms of bone metastasis from colon cancer.

Symptoms of bone metastasis from colon cancer

The first bone metastasis of colorectal cancer is rare in clinic. In the early stage, there are no symptoms. Bone isotope scan can find the diseased bones. The symptoms of bone metastasis of colorectal cancer are related to the location and quantity of tumor metastasis. For example, chest pain caused by rib metastasis is mostly manifested as pain with definite tenderness points and limited chest wall. Spinal cord metastases cause pain in the middle of the back or the affected area, while bone metastases in the limbs or trunk cause localized pain in this area. At first, bone pain is not obvious, and patients are not easy to find, but with the gradual deterioration of the disease, bone pain will aggravate, which will affect the daily activities and life of patients. Late bone metastases are mostly osteolytic lesions, so sometimes there will be pathological fractures and paralysis.

When bone metastasis occurs in colorectal cancer, most patients are in advanced stage, which not only leads to physical pain and increases the pain of patients, but also the difficulty of treatment at this time can be imagined, and cure has become an impossible task. It often takes more than one year from bone metastasis to clinical pain. Therefore, patients with colorectal cancer can not refuse clinical examination because of no pain symptoms, and exclude the symptoms of bone metastasis of colorectal cancer. Carcinomatous bone pain is characterized by fixed position, gradual aggravation of pain, and obvious at night. Early detection of bone metastasis of colorectal cancer is helpful to improve the cure rate of bone metastasis of colorectal cancer.

Although the bone metastasis of colorectal cancer is more serious, as long as the patients have confidence and can actively cooperate with the doctor's treatment, there are also opportunities for treatment, and the survival can be prolonged as far as possible. In order to prevent the occurrence of bone metastasis of colorectal cancer, patients should be treated in time at the early stage, and pay special attention to whether there is a trend of metastasis, and eliminate the impact of metastasis on patients at the later stage as soon as possible. At present, there are many imaging methods (CT, PET-CT, isotope, etc.), and fine needle aspiration is the main method for the diagnosis of suspicious lesions.

matters needing attention

The treatment of bone metastasis is the key, preoperative detailed evaluation, multidisciplinary discussion, for resectable patients, one-stage operation and postoperative adjuvant treatment can be considered, postoperative regular review is needed to effectively control the recurrence and metastasis. For unresectable patients, we can consider the evaluation after adjuvant treatment. The emergence of bisphosphonates and targeted drugs has brought new hope to patients and clinicians. Combined with radiotherapy and chemotherapy, it can reduce the toxic and side effects of radiotherapy and chemotherapy, and improve the efficacy of radiotherapy and chemotherapy. For patients with advanced cancer pain, radiotherapy and palliative chemotherapy are also effective methods to relieve pain.