How is pulmonary fibrosis to return a responsibility?

summary

Pulmonary fibrosis is the abbreviation of diffuse interstitial lung disease. We must pay attention to that pulmonary fibrosis is a kind of disease which is caused by poisons, autoimmune diseases, drug side effects, infection, severe trauma and other reasons. Persistent alveolar injury, repeated destruction, repair, reconstruction and excessive deposition of extracellular matrix lead to structural changes and functional loss of normal lung tissue. So let's take a look at what's going on with pulmonary fibrosis? What about it?

How is pulmonary fibrosis to return a responsibility?

First: Generally speaking, pulmonary fibrosis is a kind of disease caused by toxicants, autoimmune diseases, drug side effects, infection, severe trauma and other causes of lung inflammation, persistent alveolar injury, repeated destruction, repair, reconstruction and excessive deposition of extracellular matrix, which leads to structural changes and functional loss of normal lung tissue.

Second, what is the cause of pulmonary fibrosis? Pathophysiologically, the function of alveoli and capillaries gradually decreased, resulting in diffuse pulmonary interstitial fibrosis and honeycomb lung, and eventually died of respiratory failure; Under normal circumstances, the stroma is composed of a small amount of stromal macrophages, fibroblasts, myofibroblasts and lung matrix, collagen, macromolecular substances, non collagen and so on.

Third, when interstitial lung lesions occur, the weight and nature of some symptoms will change, which indicates that obvious inflammation invades the alveolar wall and adjacent alveolar wall cavity, type II alveolar epithelial cells replace type I alveolar epithelial cells, alveolar septum thickening and pulmonary fibrosis, and finally the loss of pulmonary capillaries; Pulmonary fibrosis diseases include idiopathic pulmonary fibrosis, sarcoidosis, pneumoconiosis, allergic pneumonia or radiation-induced fibrosis, collagen vascular disease-related fibrogenic alveolitis and so on.

matters needing attention

Pulmonary fibrosis diseases include idiopathic pulmonary fibrosis, sarcoidosis, pneumoconiosis (silicosis is the most serious kind of pneumoconiosis), allergic pneumonia, fibrosis caused by drugs or radiation, fibrogenic alveolitis related to collagen vascular diseases and so on.