Is chronic hemolytic anemia serious

summary

Some people with severe malnutrition will often have anemia, and the factors causing anemia are different. There are several classifications of anemia. The clinical manifestation of chronic hemolytic anemia is more obvious. Let's talk about the severity of chronic hemolytic anemia.

Is chronic hemolytic anemia serious

First: hemolytic anemia is due to the increase in the rate of destruction of red blood cells (shortened life), more than the compensatory capacity of bone marrow hematopoietic anemia. Bone marrow has 6-8 times of erythropoietic compensatory potential. If the destruction rate of red blood cells is within the compensation range of bone marrow, there is hemolysis, but there is no anemia, which is called hemolytic disease.

Second, the clinical manifestation of intravascular hemolysis is often obvious, accompanied by hemoglobinemia, hemoglobinuria and hemosiderinuria. Extravascular hemolysis mainly occurs in the spleen, the clinical manifestations are generally mild, there may be a slight increase in serum free heme, no hemoglobinuria. Although there are many kinds of hemolytic anemia, they have some of the same characteristics. The clinical manifestations of hemolytic anemia are mainly related to the duration of hemolytic process and the severity of hemolysis.

Third: chronic hemolysis is mostly extravascular hemolysis, which is characterized by anemia, jaundice and splenomegaly. Because of the long course of disease, patients with respiratory and circulatory system often have good compensation for anemia, the symptoms are mild. Due to long-term hyperbilirubinemia, patients can be complicated with cholelithiasis and liver function damage. In the process of chronic hemolysis, some inducements, such as viral infection, may cause temporary hematopoiesis arrest.

matters needing attention

From the above explanation, we can see that the incidence of chronic hemolytic anemia is relatively slow. It is mainly caused by the increase of the destruction rate of red blood cells. Patients should add more protein, so as to increase nutrition and enhance physique. This can improve anemia to a certain extent.