What is the drug for myasthenia gravis
summary
Clinical studies have found that many immune indexes in patients with this disease are abnormal. After treatment, the clinical symptoms disappear, but the abnormal immune indexes do not change. This may be an important factor for the instability and recurrence of this disease. So we must do a good job of the disease related work, then myasthenia gravis drug is.
What is the drug for myasthenia gravis
Treatment 1: oral or nasal administration, through mucosal induction of immune tolerance, can specifically reduce the antigen of local or systemic immune response. In order to prevent the occurrence of experimental autoimmune myasthenia gravis and inhibit the cellular and humoral immunity against acetylcholine receptor or its peptide, some scholars have given the eel or newborn mice acetylcholine receptor and its subunit A by oral or nasal mucosa before sensitization with acetylcholine receptor. In addition, intranasal administration can avoid the damage of gastric acid and pepsin to the antigen, which requires less antigen dose. A large number of experiments have confirmed that mucosal tolerance alone can only prevent the occurrence of experimental autoimmune myasthenia gravis, and can not effectively block the progress of experimental autoimmune myasthenia gravis.
Treatment 2: immune tolerance induced by dendritic cells, the use of immature dendritic cells, blocking or reducing the immune activation function of dendritic cells, can prevent autoimmune response. The dendritic cells of healthy rats were incubated with transforming growth factor - β 1 and transforming growth factor - γ in vitro, and then injected subcutaneously on the fifth day of experimental autoimmune myasthenia gravis. The results showed that immune tolerance was successfully induced, and the clinical symptoms of experimental autoimmune myasthenia gravis were significantly alleviated. The dendritic cells induced in vitro were the main cause of experimental autoimmune myasthenia gravis Treatment has brought new hope, but its mechanism of action in the treatment of myasthenia gravis is not clear. Moreover, dendritic cells in this state can only prevent the occurrence of experimental autoimmune myasthenia gravis, but can not effectively prevent the progress of the disease.
Treatment 3: Cyclosporin A, which is mainly used for anti rejection of liver, kidney and heart transplantation, can be used with adrenocortical hormone, and can also be used for the treatment of some immune diseases. Adverse reactions: elevated serum creatinine, hypertension, epidemic symptoms, etc.
matters needing attention
For this kind of disease: usually we must prevent the occurrence of cold, avoid wind cold, the resistance of patients with muscle weakness is very poor, if suffering from a cold, it will not only promote the recurrence or aggravation of the disease, but also reduce the collective resistance to the disease.
